ARPA-H is seeking innovative solutions for temperature-flexible storage of regenerative tissues and organs. The TIGAR exploratory topic aims to develop enabling technologies for this purpose. Solutions may involve new materials, AI/ML, high-throughput screening, biological interventions, devices, processing methods, analytical technology, and packaging. Strategies that reduce reliance on strictly controlled temperature zones are preferred. The effort has two intake groups with separate deadlines for solution video and full proposal submissions. The total ARPA-H funding requested must not exceed $2 million USD over an 18-month period of performance. Proposers must demonstrate progress towards functional preservation of tissues or organs for 30 days at practical temperatures. Full proposals will be evaluated on scientific and technical merit, proposer capabilities, contribution to ARPA-H mission, and cost. Registration in SAM. gov is required. Late submissions due to registration delays will not be considered.
The ISO closing date is February 5, 2027, 11:59 pm ET. For Intake Group 1, the solution video is due June 8, 2026, 5:00 pm ET, and the full proposal is due August 5, 2026, 5:00 pm ET. For Intake Group 2, the solution video is due December 8, 2026, 5:00 pm ET, and the full proposal is due February 5, 2027, 5:00 pm ET.
Performers will be required to register in and submit invoices for payment through the Payment Management Services (PMS) at www. ***. *. * must include a justification limited to 1,000 characters.
Full proposals will be evaluated based on overall scientific and technical merit, proposers' capabilities and/or related experience, contribution to the ARPA-H mission and relevance to the user experience, and assessment of proposed cost/price.
Eligible proposers include universities, nonprofit organizations, small businesses, and other commercial entities. Federally Funded Research and Development Centers (FFRDCs) and government entities will not be considered as prime or sub-performers, except in specific circumstances. Individuals and entities providing current professional support services to ARPA-H are ineligible for an award. Foreign entities may participate if they comply with applicable regulations.
Proposals may be rejected without further review if they do not follow ISO instructions or if concepts are out of scope. Failure to obtain or maintain an active SAM. gov registration may delay or preclude award. Failure to fully disclose an OCI or provide a mitigation plan, or failure to provide requisite research security disclosures, may result in elimination from award consideration.
The total ARPA-H funding requested must not exceed 2 million USD over the 18-month period of performance.
