The Centers for Disease Control and Prevention (CDC) intends to award a sole source contract to Temple University ALS Postmortem Core for the augmentation of ALS samples for researchers. This contract aims to establish a nationally recognized tissue core repository to advance ALS research by collecting and disseminating ALS samples. The anticipated period of performance is from May 1, 2026, through April 30, 2027, with four one-year option periods. The government is seeking to identify a nationally recognized center with extensive experience in providing high-quality ALS samples and data to academic and industry laboratories worldwide. The contractor must possess a repository of frozen and fixed CNS tissues, liver, and various muscles from ALS, MND, and non-neurologic control autopsies, along with other limited tissues. Standard operating procedures for tissue processing, quality control, and clinical data elements are required, optimized for ALS researchers. A large collection of ALS samples from the Guam cluster is also noted. This notice is not a request for competitive quotations, but any responses received by 1:00 PM ET on April 7, 2026, will be considered. The government reserves the discretion to determine whether to conduct a competitive procurement based on the responses received.
The anticipated period of performance is from May 1, 2026, through April 30, 2027, and will include four one-year option periods, as stated in the notice.
The government requires a nationally recognized center for high quality ALS samples for researchers, with extensive experience in facilitating and providing tissue samples and data to facilitate different ALS research projects in academic and industry laboratories worldwide. The contractor must have a repository compromised of: frozen and fixed CNS tissues, liver, and several muscles from ALS/MND and non-neurologic control autopsies, and a limited number of other tissues. Standard operating procedures for tissue dissection, processing, QC analysis, clinical data elements, and neuropathological characterization are specifically optimized to meet the needs of ALS researchers. A dissection method that produces the maximum number of individual, optimally sized tissue samples from each ALS relevant region, while preserving the architecture of the tissue, and a large collection of ALS samples from the Guam cluster are also required.
The government requires a nationally recognized center for high quality ALS samples for researchers. The contractor must have a repository compromised of: frozen and fixed CNS tissues, liver, and several muscles from ALS/MND and non-neurologic control autopsies. A limited number of other tissues like sural sciatic nerve, GI tract, skin, etc. , are also available. The notice also mentions a large collection of ALS samples from the Guam cluster.