Texas Tech University Health Sciences Center (TTUHSC) is seeking proposals for the custom synthesis of antibody-drug conjugates (ADCs). The project involves using a proprietary compound targeting the c-MYC oncogene as the payload for conjugation with specified antibodies. Key technical requirements include payload integration, linker selection optimization, conjugation chemistry, and purification. Deliverables include the synthesized ADC product, a certificate of analysis, and a final project report. Proposers must provide an estimated timeline for feasibility, pilot synthesis, and scale-up. Proposals are due by May 26, 2026. TTUHSC prefers online submission via the TechBid system. A HUB subcontracting plan is required. The evaluation criteria include pricing (30%), experience and reputation (20%), and product/service specifications (50%). The anticipated term of the agreement is from execution date to August 31, 2027, with an option for one 1-year renewal. Proposers must comply with all terms and conditions outlined in the RFP, including those in Appendix A (Agreement) and Appendix E (TTUHSC Vendor Information). Proposers must also complete and submit Appendix B (Execution of Offer) and Appendix D (Addenda Checklist).
The bid notice states that proposals must be submitted by 4:30 PM, Central Time on May 26, 2026. Proposals must be time stamped by the Texas Tech University Health Sciences Center Purchasing Office before the hour and date specified for receipt of solicitation.
The bid notice states that TTUHSC's standard payment terms are net 30 days.
The bid notice states that in addition to all warranties established by law, the supplier warrants that all goods and services will conform to specifications, be new, merchantable, fit for purpose, of best quality and workmanship, covered by manufacturer's warranty, and free from defects. All electrical items must meet OSHA standards and bear appropriate testing laboratory listing. TTUHSC has the right to inspect, approve, reject, and return defective goods or require reperformance of services at the supplier's expense.
The bid notice states that the award will be based on the proposal judged to be in the best interest of TTUHSC, considering price and the evaluation factors set forth in this RFP. The evaluation criteria and weights are: Proposers Pricing Proposal (30%), Proposers Experience and Reputation (20%), and Proposers Product/Service Specifications (50%).
The bid notice requires that each proposal must include information clearly indicating that the proposer meets minimum qualification requirements, including being current with the State of Texas Comptroller of Public Accounts, providing a certificate of franchise tax status, demonstrating evidence of certifications, permits, licenses, and insurances as appropriate, and being compliant with the Texas Risk and Authorization Management Program (TX-RAMP) if required. Proposers must also certify that they are not listed in specific sections of the National Defense Authorization Acts or owned by governments of countries on the U. S. Department of Commerce's foreign adversaries list.
The bid notice does not explicitly detail penalties for non-compliance, but it does state that failure to sign the execution of offer will be a basis for proposal disqualification, and a false certification can be deemed a material breach of any resulting contract, potentially leading to termination.
The bid notice provides a URL for formal protest procedures: www. ***. *. *, a specific deadline for filing a protest is not explicitly stated within the provided text.